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Broken a bone? Then don't smoke if you want it to heal.

10/11/2015 - by iMER Medical Services
For the first time, cigarette smoking is linked to a major decrease in the concentration of bone marrow progenitor cells. Orthopedic surgeons in Jerusalem linked cigarette smoking to a major decrease in the concentration of bone marrow progenitor cells (BMPCs), which significantly impairs the healing of bone fractures and hinders bone repairing operations. Prof. Meir Liebergall, chairman of the orthopedic surgery department at Hadassah-University Medical Center in Jerusalem’s Ein Kerem, just published his team’s findings in the journal Bone Marrow Research.

Working with colleagues Shaul Beyth, Rami Mosheiff, Ori Safran and Anat Daskal, Liebergall said it is already known that tobacco consumption is associated with musculoskeletal degenerative disorders, delayed fracture healing and failure for bone tissues to unite. BMPCs are known to express CD105 (endoglin), a protein that is central to musculoskeletal healing and regeneration. The researchers thus hypothesized that smoking is associated with lower levels of BMPCs. Samples were collected from consenting patients aged 18 to 65 during the first steps of pelvic surgery.

Thirteen smokers and 13 nonsmokers of comparable age and gender were included in the study, while patients with active infectious or cancer, a history of cytotoxic or radiation therapy, primary or secondary metabolic bone disease or bone marrow dysfunction were excluded. Liebergall noted that “relatively little research has been performed with the aim of studying the effects of smoking on the musculoskeletal system,” as opposed to other organ systems.

BMPCs, also known as multipotent mesenchymal stromal cells, are rare multipotent cells residing in all musculoskeletal tissues that serve as a reservoir for tissue regeneration, the researchers wrote. Due to their capability for multipotent differentiation into specialized cells, and their secretion of a wide range of bioactive molecules, they are central to healing and regeneration, they continued. “Since these cells are rare, it has been difficult to isolate them in quantities that are large enough to evaluate their concentration,” the Hadassah team said. Nonetheless, they managed to develop a safe and effective method.

The study was designed to determine the effect of smoking a pack of cigarettes daily on the BMPC cell population in bone marrow. They found a “significantly lower concentration” of BMPC cells in smokers’ bone marrow, compared to nonsmokers’ bone marrow.

This reduced cell population, they concluded, can lead to reduced bone regeneration in smokers, “with potentially important implications for physiological maintenance and repair in the musculoskeletal system.”

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iMER (www.imer.biz) is the international patients office of the Hadassah University Hospital in Jerusalem. iMER, with offices in Cyprus, Austria, Germany, Israel, Russia, Ukraine, Azerbaijan and Georgia, in cooperation with Hadassah, offers patients assessment services, the preparation of a medical plan and referral to the appropriate Hadassah units.
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  • 02/02/2015 - by Vasiliki Veneti, Post MA

    H Veneti Counseling, Psychotherapeutic and Training Services Ltd σας προσκαλεί στην εκδήλωση που διοργανώνει για την Παρουσίαση του Προγράμματος Εξειδίκευσης στην Θεραπεία των Διαταραχών της Προσωπικότητας την Παρασκευή 6 Φεβρουαρίου στις 21:00 στο ξενοδοχείο Centrum Hotel, Οδός Πασικράτους 15, Πλατεία Ελευθερίας στην Λευκωσία.



    Παρασκευή 6 Φεβρουαρίου 2015

  • 02/02/2015 - by Vasiliki Veneti, Post MA

    ΣΕΜΙΝΑΡΙΟ ΜΕ ΘΕΜΑ: «ΚΡΙΣΕΙΣ ΠΑΝΙΚΟΥ: ΣΥΜΠΤΩΜΑΤΟΛΟΓΙΑ, ΑΙΤΙΕΣ, ΤΕΧΝΙΚΕΣ ΔΙΑΧΕΙΡΙΣΗΣ» ώρα 18:00-20:30, στο Centrum Hotel

    Παρασκευή 6 Φεβρουαρίου 2015

  • 09/12/2014 - by Vasiliki Veneti, Post MA

    H Veneti Counseling, Psychotherapeutic and Training Services Ltd σας προσκαλεί στην εκδήλωση που διοργανώνει για την Παρουσίαση του Προγράμματος Εξειδίκευσης στην Θεραπεία των Διαταραχών της Προσωπικότητας την Παρασκευή 6 Φεβρουαρίου στις 21:00 στο ξενοδοχείο Centrum Hotel, Οδός Πασικράτους 15, Πλατεία Ελευθερίας στην Λευκωσία.

    Η είσοδος είναι ελεύθερη!
    Απαραίτητη η δήλωση συμμετοχής.

    ΠΑΡΟΥΣΙΑΣΗ ΠΡΟΓΡΑΜΜΑΤΟΣ ΕΞΕΙΔΙΚΕΥΣΗΣ ΣΤΗ ΘΕΡΑΠΕΙΑ ΤΩΝ ΔΙΑΤΑΡΑΧΩΝ ΤΗΣ ΠΡΟΣΩΠΙΚΟΤΗΤΑΣ

  • 09/12/2014 - by Vasiliki Veneti, Post MA

    ΗΜΕΡΟΜΗΝΙΑ ΔΙΕΞΑΓΩΓΗΣ: Παρασκευή 6 Φεβρουαρίου 2015, 18:00-20:30

    ΤΟΠΟΣ ΔΙΕΞΑΓΩΓΗΣ: Centrum Hotel, Οδός Πασικράτους 15, Πλατεία Ελευθερίας, Λευκωσία, Κύπρος

    Το σεμινάριο ενημερώνει τους συμμετέχοντες για τα κλινικά συμπτώματα των κρίσεων πανικού, τις αιτίες πυροδότησης ενώ προτείνει τεχνικές οι οποίες είναι ιδιαίτερα αποτελεσματικές στην διαχείριση των κρίσεων πανικού. 

    Το σεμινάριο απευθύνεται σε κάθε ενδιαφερόμενο που επιθυμεί να ενημερωθεί για τις κρίσεις πανικού. 

    ΚΟΣΤΟΣ ΣΥΜΜΕΤΟΧΗΣ: 25€

    ΣΕΜΙΝΑΡΙΟ ΜΕ ΘΕΜΑ: «ΚΡΙΣΕΙΣ ΠΑΝΙΚΟΥ: ΣΥΜΠΤΩΜΑΤΟΛΟΓΙΑ, ΑΙΤΙΕΣ, ΤΕΧΝΙΚΕΣ ΔΙΑΧΕΙΡΙΣΗΣ»

 

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